The 23-year-old Dominican outfielder raced backwards to claim Texas batter Brandon Nimmo's fly ball, colliding with his head and shoulder against an outfield LED video advertising board covered by a chain-link fence in left field.
Dominguez stayed down on the field for around a minute, tended to and examined by medical staff. He was able to slowly walk to a cart, receiving cheers from the crowd, before he was taken away for further treatment.
There was no immediate word from the Yankees on his condition.
Despite the forceful collision, Dominguez was able to hold onto the ball, giving the Yankees their first out of the game.