Ethan de Groot is restored to the front row at loosehead in place of George Bower, while Jordie Barrett returns from injury at centre in place of Timoci Tavatavanawai.
Bower and Tavatavanawai are named among the replacements, where there are three other changes from the 43-21 win over Australia in Sydney on October 17.
Asafo Aumua is chosen ahead of the injured Samisoni Taukei'aho as hooker replacement, while Christian Lio-Willie replaces Shannon Frizell, who is also injured, and Anton Segner is preferred to Duplessis Kirifi, who was not chosen for the month-long trip to Britain.
New Zealand are unbeaten in 33 past tests against Scotland, with 31 wins and two draws.
Team: 15-Beauden Barrett, 14-Will Jordan, 13-Quinn Tupaea, 12-Jordie Barrett, 11-Josh Moorby, 10-Damian McKenzie, 9-Cam Roigard, 8-Wallace Sititi, 7-Peter Lakai, 6-Tupou Vaa’i, 5-Fabian Holland, 4-Scott Barrett, 3-Fletcher Newell, 2-Codie Taylor (captain), 1-Ethan de Groot
Replacements: 16-Asafo Aumua, 17-George Bower, 18-Pasilio Tosi, 19-Christian Lio-Willie, 20-Anton Segner, 21-Cortez Ratima, 22-Timoci Tavatavanawai, 23-Rieko Ioane