Leeds duo Dominic Calvert-Lewin and Anton Stach are doubts to face Tottenham and are both expected to be game-time decisions.
Elsewhere, Ryan Gravenberch is at risk of missing Liverpool's fixture at Crystal Palace after missing their Champions League defeat to Fenerbahce with a heel injury.
See who's missing for the next round of Premier League fixtures
Everton vs Coventry (Friday, 21:00 CET)
WON'T PLAY
Everton: Jack Grealish (coach's decision)
Coventry: Aurele Amenda (calf injury), Josh Eccles (ankle injury), Luke Woolfenden (knee injury), Haji Wright (muscle injury)
DOUBTFUL
Frank Onyeka (groin injury), Bobby Thomas (calf injury)
Everton's summer recruit Hayden Hackney has lost a career-high six head-to-heads against Coventry and has been at the thick of the action across his last five league meetings (A1, YC4, RC1).
Coventry's Taiwo Awoniyi may have been on target last weekend against Sunderland, but his seven club goals prior all came on the road.
Everton's Tyrique George picked up a late knock against Newcastle, while Coventry's defensive lynchpin Bobby Thomas missed the win against Sunderland.
Leeds vs Tottenham (Saturday, 13:30 CET)
WON'T PLAY
Leeds: Mateo Joseph (knee injury)
Tottenham: Mykhailo Mudryk (ankle injury), Wilson Odobert (knee injury), Savio (muscle injury), Xavi Simons (knee injury)
DOUBTFUL
Dominic Calvert-Lewin (foot injury), Noah Okafor (groin injury), Joe Rodon (muscle injury), Anton Stach (foot injury), Tosin Adarabioyo (calf injury), Lucas Bergvall (knee injury)
Leeds striker Dominic Calvert-Lewin has scored or assisted in three of his last five appearances against Tottenham, with his club picking up points in all three (W1, D2).
Mathys Tel rounded off Spurs' win away to Chelsea and has now scored six of his eight goals for the club after half-time, including against Leeds last season.
Noah Okafor is a doubt after missing Leeds' last match with a groin problem, whilst Tottenham will assess Lucas Bergvall and Tosin Adarabioyo closer to matchday.
Arsenal vs Hull (Saturday, 16:00 CET)
WON'T PLAY
Arsenal: Max Dowman (red card), Bukayo Saka (thigh injury)
Hull: Matt Crooks (yellow cards), Charlie Hughes (groin injury), Eliot Matazo (knee injury), Hidemasa Morita (muscle injury), Matt Targett (ankle injury)
DOUBTFUL
Ezri Konsa (knee injury), Ilyas Ansah (back injury), Lucas Gourna-Douath (calf injury)
Declan Rice has five open-play Premier League assists this season, the most he's ever recorded in one campaign, with three of the last four of those coming after the 55th minute.
Oliver McBurnie became the first player to score a direct free-kick in the Premier League for Hull since December 2016 when doing so against Ipswich (D 2-2), while three of his last four goals came after the hour mark.
Max Dowman is suspended for Arsenal, while the same goes for Hull's Matt Crooks.
Fulham vs Newcastle (Saturday, 16:00 CET)
WON'T PLAY
Fulham: Tom Cairney (knee injury)
Newcastle: Ewen Jaouen (muscle injury), Joelinton (muscle injury), Valentino Livramento (knee injury), Jacob Ramsey (red card)
DOUBTFUL
Matias Fernandez-Pardo (illness)
Only three players start the round having had more touches in the opposition box than Fulham's Oscar Bobb (50), whose last five goals for club or country have come in the first or final 15 minutes.
Newcastle's Harvey Barnes has scored three times on his last four Premier League visits to Craven Cottage, while six of his last eight Premier League strikes came after half-time.
Fulham look to have no fresh issues, while Newcastle's absentee list now includes the suspended Jacob Ramsey.
Nottingham Forest vs Manchester City (Saturday, 18:30 CET)
WON'T PLAY
Nottingham Forest: Nicolas Dominguez (muscle injury), Nicolo Savona (knee injury)
Manchester City: Antoine Semenyo (knee injury)
DOUBTFUL
Igor Jesus (calf injury)
Morgan Gibbs-White is set to make his 200th Premier League appearance here, with his 151 for Forest representing the third-most for the club in the competition - he assisted the winner in their only head-to-head victory since promotion.
City's Erling Haaland leads the way in the Premier League with nine goals, four of which were match openers, but he's not been involved in a goal in the last three league head-to-heads.
Neither side seemingly have any fresh injury concerns.
Brighton vs Brentford (Sunday, 15:00 CET)
WON'T PLAY
Brighton: Evan Ferguson (ankle injury), Kaoru Mitoma (hamstring injury), Stefanos Tzimas (knee injury), Zadok Yohanna (injury)
Brentford: Fabio Carvalho (injury), Jay Dasilva (muscle injury), Kaye Furo (surgery), Rico Henry (hip injury), Antoni Milambo (knock)
DOUBTFUL
Femi Azeez (abdominal strain), Ferdi Kadioglu (hip injury), Pascal Struijk (rest)
Pascal Gross has created a Premier League-high 24 chances this season, while only three other players can boast a higher return of goal contributions than his seven (G3, A4).
He also scored and assisted in his latest home appearance against the Bees. Often utilised from the bench,
Brentford's Callum Wilson has only contributed to more Premier League goals against West Ham than he has against Brighton (G5, A4).
Ferdi Kadioglu remains absent for Brighton, while Brentford seemingly have no fresh injury concerns.
Crystal Palace vs Liverpool (Sunday, 15:00 CET)
WON'T PLAY
Crystal Palace: Jean-Philippe Mateta (red card), Chadi Riad (knee injury), Ismaila Sarr (groin injury), Takehiro Tomiyasu (calf injury)
Liverpool: Conor Bradley (knee injury), Hugo Ekitike (Achilles tendon injury), Jeremie Frimpong (muscle injury), Giovanni Leoni (knee injury), Amara Nallo (leg injury)
DOUBTFUL
Ryan Gravenberch (heel injury)
Yeremy Pino tends to grow into the game, with six of his nine goals for Palace coming after half-time, the first of which was against Liverpool last season.
He may be in contention with Liverpool's Florian Wirtz, who has scored each of his last seven for club and country after half-time too - since the start of February he's only scored one Premier League goal, which actually came against Crystal Palace.
Palace will be missing two of their most prominent attacking options in Ismaila Sarr and Jean-Philippe Mateta, while Liverpool's Ryan Gravenberch will be monitored having missed their midweek game.
Ipswich vs Bournemouth (Sunday, 15:00 CET)
WON'T PLAY
Ipswich: None confirmed
Bournemouth: Julian Araujo (thigh injury), Juanlu Sanchez (ankle injury), Alex Toth (muscle injury)
DOUBTFUL
Jack Taylor (knee injury), Veljko Milosavljevic (lacking match fitness), Alex Scott (thigh injury)
Ipswich's Julio Enciso has scored in Ipswich's last two matches, with his last four goals for club or country coming in games that finished level after 90 minutes.
Bournemouth's Evanilson has already eclipsed his Premier League goal contribution tally for last season (G6, A1) with the eight he's racked up so far (G4, A4) - none of his last seven competitive goals for the Cherries arrived before the 30th minute.
Ipswich hope to see Sasa Lukic return from injury here, a sentiment shared by Bournemouth with Alex Scott.
Sunderland vs Chelsea (Sunday, 15:00 CET)
WON'T PLAY
Sunderland: Omar Alderete (red card), Daniel Ballard (muscle injury), Habib Diarra (muscle injury), Romaine Mundle (knee injury)
Chelsea: Aaron Anselmino (injury), Jamie Gittens (ankle injury), Reece James (knee injury), Joao Pedro (thigh injury), Maxence Lacroix (muscle injury)
DOUBTFUL
Nordi Mukiele (concussion), Moises Caicedo (inactive), Jorrel Hato (injury), Geovany Quenda (muscle injury)
Three of Trai Hume's last four Sunderland goals were first-half match openers, including his strike in last season's corresponding fixture.
Pedro Neto laid on the assist for both of Chelsea's head-to-head goals last term and has scored nine of his last 11 goals for the Blues on the road.
Sunderland's Omar Alderete is suspended, but Nordi Mukiele is nearing a return. Chelsea are still without Joao Pedro, but could welcome back Emiliano Martinez and Jordan Henderson here.
Manchester United vs Aston Villa (Sunday, 17:30 CET)
Information to be confirmed.