Liverpool's march towards the title continued with a 2-0 win over Newcastle to move 13 points clear of Arsenal, who were held to a 0-0 draw by Nottingham Forest.
Manchester City halted Tottenham's recent uptick in form with a 1-0 win in north London while their rivals Manchester United survived a red card to eventually beat Ipswich 3-1.
Elsewhere, Chelsea thrashed relegation-bound Southampton 4-0 and Crystal Palace recorded an impressive 4-1 victory over Aston Villa.
Based on Flashscore's player ratings, here's the latest Premier League Team of the Week.
Goalkeeper
Ederson (Manchester City) 8.0
Ederson registered six saves and a clean sheet on the way to Manchester City's victory at Tottenham.
The Brazilian didn't have to pull off anything too major but was equal to Spurs' chances when he needed to.
Defence
Jake O'Brien (Everton) 8.4
Jake O'Brien opened his Everton account with a super header to help the revived Toffees earn a 1-1 draw against Brentford.
The Republic of Ireland defender snuck in at the back post and stooped low to direct his effort into the corner beyond the goalkeeper.
Harry Maguire (Manchester United) 8.3
Harry Maguire helped to dig Manchester United and Ruben Amorim out of a hole as he scored what turned out to be the winner against Ipswich.
Maguire also came away from the win at Old Trafford with seven clearances, three blocks and two tackles.
Levi Colwill (Chelsea) 8.4
Levi Colwill took control in central defence as Chelsea dismantled Southampton at Stamford Bridge.
Colwill got on the scoresheet with a thumping header and also completed a game-high 78 passes in the win.
Marc Cucurella (Chelsea) 8.3
Colwill's fellow Chelsea defender Marc Cucurella also had an enjoyable evening against Southampton as he too found the back of the net.
The Spaniard completed the rout with a fine strike into the corner to round out a comfortable evening.
Midfield
Pedro Neto (Chelsea) 8.2
Pedro Neto was given a more attacking role against Southampton and it certainly paid dividends.
Neto doubled Chelsea's lead with a powerful near-post shot before turning provider with his free-kick being met by Colwill.
Adama Traore (Fulham) 8.3
The rapid Adama Traore impressed against his former side as the Spaniard helped Fulham over the line to a 2-1 win on their trip to Wolves.
Traore assisted Rodrigo Muniz's game-winning goal with a super curling pass which split open the Wolves back line.
Justin Kluivert (Bournemouth) 8.7
Bournemouth's man of the moment Justin Kluivert was at it again as he scored his 12th Premier League goal of the season in a 2-1 defeat to Brighton.
The Cherries' Dutchman levelled the game for the visitors with a right-footed rocket into the corner after cutting inside.
Ryan Sessegnon (Fulham) 8.1
Ryan Sessegnon scored his first Fulham goal in six years after returning to the club as he netted in their win over Wolves.
Sessegnon grabbed a rare starting opportunity with both hands as he surged forward to fire in the game's opener after just 59 seconds.
Attack
Rodrigo Muniz (Fulham) 8.4
Rodrigo Muniz had a pivotal role for Fulham as he keyed the game-winner for them against Wolves.
Brazilian Muniz latched onto the end of a great ball from Traore before calmly lifting his effort over the onrushing Jose Sa into an empty net.
Christopher Nkunku (Chelsea) 7.9
The fourth Chelsea player in this week's team is Christopher Nkunku, who had a hand in two of the Blues' four goals.
The Frenchman got the scoring underway with an effort at the back post before teeing up Neto for his strike.