Spurs are in 12th place in the Premier League at the halfway point of the campaign with a massive injury list decimating Ange Postecoglou's squad.
They have one win in eight league games but have back-to-back victories before nipping down to the Emirates Stadium – one against Liverpool in the EFL Cup and an FA Cup triumph over non-league Tamworth after extra time.
Those results epitomise the wacky nature of Tottenham's season and Arsenal run the risk of seeing theirs completely fall apart after a challenging week.
The Gunners were beaten 2-0 at home to Newcastle in the first leg of their EFL Cup semi-final before crashing out of the FA Cup on penalties to Manchester United, who were down to 10 men for nearly an hour.
Mikel Arteta's team are still second in the Premier League and will be favourites ahead of Spurs' arrival, but there could be cause for some optimism that the visitors could damage the hosts' title ambitions.
Kinsky's instant impact
One of the major absentees Tottenham have had to deal with through their injury crisis has been the loss of first-choice goalkeeper Guglielmo Vicario.
The Italy international has been working his way back to fitness after fracturing his ankle in November, allowing his backup Fraser Forster to step up to the plate.
Performances have been hit and miss but even he was out for one game through illness which forced Spurs to play third-choice Brandon Austin.
They acted by signing Czech starlet Antonin Kinsky, who was thrust straight into action just a few days after joining in their 1-0 EFL Cup semi-final win over Liverpool.
It was a good display from the 21-year-old as he showcased some superb ball-playing and a presence from set pieces, which he also displayed in his clean sheet at Tamworth.
It's still early days of course, but Kinsky has certainly thrown his hat in the mix to establish himself as Spurs' main option in goal.
The way he plays seems to have given Postecoglou's men a bit more composure at the back – especially with their makeshift defensive line.
That will be a necessity in an expectant hostile atmosphere at Arsenal where errors could creep into the game.
Solanke ticking along
An impact has been made at the opposite end for Tottenham too with Dominic Solanke establishing himself as a key asset up front.
Solanke joined Spurs in the summer for a big £65 million fee from Bournemouth after a 21-goal campaign for the Cherries.
Spurs have needed someone to fill the gaping hole left behind by Harry Kane and while Solanke isn't of that ilk, he has been making inroads of his own.
The 27-year-old has 11 goals and six assists across all competitions this term but has often been involved in games when not on the stats sheet.
Much of Solanke's success is down to his tireless pressing which suits Postecoglou's style perfectly, while he is also someone to target if Spurs want to simplify.
That was demonstrated in their 2-1 defeat to Newcastle when he brilliantly headed in Pedro Porro's cross and against Liverpool when he latched onto the Spaniard's long ball and fed in Lucas Bergvall for the winner.
So Spurs may want to tap into that kind of hold-up play against Arsenal, who have two of the most imposing central defenders in William Saliba and Gabriel.
Arsenal's own concerns
While Tottenham's issues have been well-documented, Arsenal aren't in a particularly stable shape themselves with injuries also starting to hit them.
Riccardo Calafiori has emerged as a new worry after joining defenders Ben White and Takehiro Tomiyasu on the sidelines, but it's going forward where the problems are mounting.
Bukayo Saka is the biggest blow having been out for nearly a month now, his understudy Ethan Nwaneri is also crocked and their misery is compounded by Gabriel Jesus likely out for the rest of the season with a knee injury.
And the current crop of forwards available to Arteta have been unable to take their chances – an issue laid threadbare in their last two outings.
Arsenal had an expected goals (xG) figure in excess of 3.0 in their EFL Cup defeat to Newcastle and failed to score and Kai Havertz was guilty of wasting golden opportunities against Manchester United on Sunday.
Tottenham have endured a torrid time at the Emirates since Arsenal moved there in 2006 coming away with just one win 14 years ago, but they could spring a surprise.
Postecoglou will be unbothered by what is happening on the other side of the fence but recent developments show Arsenal are very much beatable if the pieces come together.